PANCREATIC ISLET TRANSPLANTATION AND REGENERATION FOR Diabetes mellitus TREATMENT
نویسندگان
چکیده
The pancreas contains exocrine, endocrine, and ductal cells and serves two major functions: (a) the production of digestive enzymes, such as amylase and lipase, which are secreted by exocrine acinar cells and routed to the intestine by a branched ductal network; and (b) the regulation of blood sugar, which is achieved by endocrine cells of the islets of Langerhans. The endocrine cells, arranged in islets within the pancreas, consist of alpha, beta, delta, and PP or gamma cells, which secrete peptide hormones glucagon, insulin, somatostatin, and pancreatic polypeptide (PP), respectively (Menger et al., 1994).
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